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Deubiquitizing Enzyme for the Division of Preclinical Innovation - Purchase Descripiton Attachment

General Information

Document Type:PRESOL
Posted Date:Aug 18, 2017
Category: Chemicals and Chemical Products
Set Aside:N/A

Contracting Office Address

Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 6001 Executive Boulevard, Room 3165, Bethesda, Maryland, 20892, United States


Purchase Description Attachment PUBLIC NOTICE OF PROPOSED ACQUISITION National Institute on Drug Abuse, Office of Management, Office of Acquisition Neurosciences Consolidated Operation Acquisition Center (COAC) ________________________________________ (FAR Subparts 5.101(a) (2) & 13.105) Announcement Number: HHS-NIH-NIDA-SSSA-NOI-2017-743 Date Notice Posted: August 18, 2017 Date Notice Expire: August 23, 2017 Date Responses Due: August, 23 2017, 5 PM Eastern Standard Time Proposed Award Date: August 31, 2017 Project Title: Deubiquitizing Enzyme for the Division of Preclinical Innovation Contracting Office: National Institute on Drug Abuse (NIDA), Neurosciences Consolidated Operation Acquisition Center (COAC), Office of Acquisition (OA), Station Support Contracts and Simplified Acquisition Branch (SS/SA) Contact Points: Contracting Officer: Rachelle Trice, 301-827-6732/rachelle.trice@nih.gov Contract Specialist : Michelle Morelli, 301-827-0914/michelle.morelli@nih.gov ________________________________________ Acquisition Authority: This acquisition is being conducted under Federal Acquisition Regulations (FAR) Part 13 - Simplified Acquisition Procedures, and the resultant contract award will include all applicable provisions and clauses in effect through Federal Acquisition Circular 05-95, dated 01-19-2017. North American Classification System (NAICS) Code: 325199 Small business size standard: 1,250 Classification Code: 68 - Chemical and Chemical Products Set-aside Status: This proposed acquisition is considered sole-source. Competition Status: This requirement is posted as non-competitive. Description: The purpose of this acquisition is to acquire 40, 25ug vials of 6XHIS-USP16 enzyme. The USP16 project aim is to develop a potent and selective inhibitor of USP16 for the purpose of developing a Downs Syndrome and Alzheimers Disease therapeutic. USP16 is an active deubiquitizing enzyme encoded on chromosome 21, trisomy of which causes Downs Syndrome (DS). Increased USP16 protein levels in people with DS may contribute to the development of certain phenotypes of DS. The Division of Preclinical Innovation (DPI) requires 6XHIS-USP16 enzyme to optimize assays and locate the proper inhibitor. The Government will award a purchase order resulting from this Request For Quotation (RFQ) to the responsible offeror whose offer conforming to the RFQ will be most advantageous to the Government, price and other factors considered. Refer to attached "Purchase Description Attachment" for the enzymes salient characteristics, quantity, delivery date and evaluation criteria. Summary Statement: All responses to this request for quotation must be received by 5 PM Eastern Standard Time, on August 23, 2017 and must reference the announcement number specified above. Responses may be submitted electronically to Michelle Morelli, Contract Specialist, at michelle.morelli@nih.gov Fax responses will not be accepted. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All respondents must have an active registration in the System for Award Management (SAM) www.sam.gov. Closing Statement: All responsible sources may submit response which, if timely received, must be considered by the agency.

Original Point of Contact

POC Michelle C. Morelli, Phone: 3018270914

Place of Performance

Link: FBO.gov Permalink
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